脑卒中是一种对人类健康具有巨大危害的脑血管疾病，人类针对这种疾病提出了许多治疗方案，其中，神经介入手术作为一种预防和治疗脑卒中的方法，因其具有微创、治疗精准等优点获得了越来越广泛的关注。随着神经介入手术不断的发展和优化，传统神经介入器械缺乏生命体征感知能力的问题愈发突出，临床医生迫切希望在术中能够对手术区域的血氧饱和度、血液流速进行感知，而常用的医疗监护仪器由于缺少针对神经介入手术的专门考量，难以满足医生对血氧饱和度、血氧流速的术中原位精准监测的要求。针对上述问题，我利用光纤作为传感器平台，利用两种血红蛋白的吸收光谱差异实现了对血氧饱和度的监测，同时利用荧光示踪法实现了对血液流速的检测。更进一步的，结合两种传感器的功能和手术的要求，我设计了适用于神经介入手术的复结构柔性光纤，并设计了适用于该光纤探针的外围配套测量设备，从而构建了完整的光纤传感器系统。在后面的实验过程中，我首先在实验室条件下验证了该系统的可行性，并针对两种功能进行了标定测试，之后，我使用该光纤传感器系统进行了动物实验，验证了该系统在实验动物上的功能有效性。

Stroke is a cerebrovascular disease with great harm to human health, and human beings have proposed many treatment options for this disease, among which, neurointerventional surgery as a method of preventing and treating stroke has received more and more attention because of its advantages of minimally invasive and precise treatment.With the continuous development and optimization of neurointerventional surgery, the problem of traditional neurointerventional instruments lacking vital sign perception has become more and more prominent, clinicians are eager to perceive the blood oxygen saturation and blood flow rate in the surgical area during surgery, and the commonly used medical monitoring instruments are difficult to meet the requirements of doctors for intraoperative and in-situ accurate monitoring of blood oxygen saturation and blood oxygen flow rate due to the lack of special considerations for neurointerventional surgery.In response to the above problems, I used optical fiber as a sensor platform, used the difference in absorption spectra of the two hemoglobins to monitor blood oxygen saturation, and used fluorescence tracing method to detect blood flow rate. Further, combining the functions of the two sensors and the requirements of surgery, I designed a complex-structure flexible optical fiber suitable for neurointerventional surgery, and designed a peripheral supporting measurement equipment suitable for the optical fiber probe, so as to build a complete optical fiber sensor system.In the subsequent experiment, I first verified the feasibility of the system under laboratory conditions and performed calibration tests for both functions, and then I conducted animal experiments using this fiber optic sensor system to verify the functional effectiveness of the system on laboratory animals.