新能源作为七大战略新兴行业之一，电气化和智能化的双重创新叠加，正在发生巨大变革。蔚来汽车作为互联网造车新势力之一，其发展经历了从初创到崛起、低谷、转折，在跨界的创新过程中，蔚来汽车实际上在走过了一条以用户为中心，战略重构各方资源的整合创新之路。其创新具有全球视野下的开放性，全产业链、全员、全要素参与的全面性，与供应商共生共荣的协同性，与产业、政策良性互动的生态性等特征，是根据中国的具体市场与国情做出的符合中国实际的创新方案。蔚来汽车的整合创新之路实际上是一个入圈与破圈的双向重构过程。蔚来汽车作为我国新能源汽车造车新势力的典型代表，同时又代表了一种新的商业模式，即战略引领、以用户为中心、开放式研发、生态建构为支撑的整合式创新模式。虽然蔚来汽车也面临一系列挑战，但其整合式创新模式有望引领国内造车新势力的发展。

Taking NIO as a case, this article makes a detailed and comprehensive study of NIO's business model from the perspective of holistic innovation. NIO's innovation road is supported by a user-centered strategy, open independent research and development, and builds an industrial ecology through investment and other means, and co-create and co-build with suppliers. In general, NIO has built a comprehensive, coordinated, collaborative, and ecological holistic innovation road. This article also summarizes the industrial opportunities brought by the new energy industry to Chinese innovative companies from the industrial perspective. Through literature analysis, in-depth interviews and other research methods, this paper reproduces the holistic innovation path of NIO from multiple angles.As one of the seven strategic emerging industries, the new energy vehicle is undergoing great changes with the electrification and the intellectualization meanwhile. NIO has experienced a transition from start-up to rise, trough and turning point. In the process of cross-border innovation, NIO has actually gone through a holistic innovation road of user-centered and strategic reconstruction of various resources. Its innovation is characterized by openness from a global perspective, comprehensive participation of the whole industry chain, all employees and all factors, symbiosis and co-prosperity with suppliers, and ecological interaction with industries and policies. It is an innovation roadmap made according to China's specific market and national conditions in line with China's reality. NIO's road of holistic innovation is actually a two-way reconstruction process of entering and breaking the ecosystem.As a representative of new energy vehicle manufacturers in China, NIO represents a new business model, which is a holistic innovation model with strategic guidance, user-centered orientation, open research and development and ecological construction as the support. Although NIO still faces a series of challenges, its holistic innovation model is expected to lead the development of new domestic car manufacturing forces.